All 8 of the individuals in the diagram may have safe sex with each other if none of them are diseased or fertile. Now, you can't leave the set, but any one of the eight could fuck anyother one and no one would get sick or pregnant.
Now, if we don't know about 1,3 and 6's disease and fertility status, 2,4,5, 7 and 8 can still fuck with impunity. This is fourth grade set theory applied to determining to whom you can fluid bond.
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